This package is for anyone who experiences musculoskeletal pain, has a predisposition to bone disease such as osteoporosis , or for women who have prematurely entered menopause. And for those who want to have the condition of their bones checked.
The bone health test has been designed specifically for people with musculoskeletal pain and a predisposition to osteoporosis - especially post-menopausal women. They offer a bone metabolism analysis including calcium, phosphorus, vitamin D, hormone levels and other key parameters to determine bone health.
This package is for anyone who experiences musculoskeletal pain, has a predisposition to bone disease such as osteoporosis , or for women who have prematurely entered menopause.…
This package is for anyone who experiences musculoskeletal pain, has a predisposition to bone disease such as osteoporosis , or for women who have prematurely entered menopause. And for those who want to have the condition of their bones checked.
The bone health test has been designed specifically for people with musculoskeletal pain and a predisposition to osteoporosis - especially post-menopausal women. They offer a bone metabolism analysis including calcium, phosphorus, vitamin D, hormone levels and other key parameters to determine bone health.
Benefits of Bone health
Comprehensive testing: Includes a wide range of tests for key bone metabolism parameters.
Osteoporosis Prevention: Osteoporosis can be prevented by early detection of risks and bone turnover disorders followed by appropriate treatment.
Promoting overall health: Includes testing of the liver, kidneys and immune system.
Individual results: test tailored to men and women, taking into account hormonal changes.
Detailed diagnostics: results provide an in-depth view of bone health and help develop a treatment plan.
Notice
The definitive diagnosis is determined by a physician, based on further tests.
Recommendations regarding blood collection: For the blood test, ensure you fast beforehand and avoid alcohol and smoking. Bring a 10 ml sample of the entire volume of your first morning urine, not the mid-stream urine.
What’s inside
Calcium
Calcium is a mineral and also an essential building block of bones and teeth. It participates in the function of a number of enzymes, blood clotting, muscle function and the production and release of…
Phosphate is an important mineral that helps with various functions, including bone health, teeth, energy production, and cell communication. Abnormal phosphate levels could indicate certain medical…
CBC allows to detect anemia and thus impaired oxygen supply to tissues, exclude infection or malfunction of the immune system and suspect blood clotting disorders or the risk of blood clots.
C-reactive protein (CRP) is a protein synthesised in the liver in response to an increase in plasma concentration of IL-6 in particular, and to a lesser extent other pro-inflammatory cytokines. It is…
Vitamin D (calciferol) is present in humans in two different forms: vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol). You can use our test to measure your vitamin D blood level. Vitamin…
Bone is a metabolically active organ where there's a continual cycle of old bone breakdown and new bone tissue formation. The whole process is controlled by hormones and growth factors [1,2]. Bones play many important roles in the human body. Changes in bone metabolism can happen at various life stages and might be linked to other conditions, treatments, as well as the natural ageing process. The most widely recognised metabolic bone disorder is osteoporosis [3].
The test should be conducted in cases of dull, vague back pain, particularly between the shoulder blades and in the lumbar region, as well as reduced or restricted mobility, bone pain during everyday activities such as sitting or standing, fatigue, weakness, malaise, and joint and muscle pain. This package is suitable for those who want to check the health of their bones.
What the test of osteoporosis includes
Bone health BASIC includes basic parameters that provide information about bone metabolism. In addition to determining the levels of calcium and phosphorus, the test includes total level of ALP (alkaline phosphatase), hormones such as osteocalcin and vitamin D, and marker CRP (C-reactive protein) and bone markers Beta-CrossLaps and P1NP. The test is complemented by a complete blood count with a differential count.
Calcium
Calcium plays crucial roles in the body. It's responsible for the hardness and strength of human bones, contributes to the proper function of the nervous and muscular systems, and is essential for heart function and blood clotting. The largest reserve of calcium, approximately 99%, is stored in the bones and teeth.
Phosphorus
Phosphorus, in its inorganic form bound as calcium phosphate and hydroxyapatite, constitutes a component of bones and teeth. In its organic form, phosphorus is crucial for the proper functioning of muscles, the nervous system, energy production, and the maintenance of the internal environment of human body.
ALP
ALP, alkaline phosphatase, is an enzyme that influences the metabolism of high-energy phosphate bonds and assists in the transport of inorganic phosphate across the cell membrane. It is mainly found in bone and liver cells.
Blood counts
Blood counts and differential leukocyte counts can help rule out infection and immune system disorders, detect anaemia which can indicate impaired oxygen supply to tissues, and raise suspicion of a clotting disorder or risk of blood clots.
CRP
CRP is one of the acute phase reactants and is a component of the body's immune defense system. As a useful indicator with good dynamics, it is especially helpful in tracking infections/inflammation.
Vitamin D
Vitamin D is a crucial fat-soluble vitamin that serves vital functions in the human body. It's essential for the proper growth and development of bones and teeth, as it stimulates bone formation by activating osteoblasts to synthesise collagen and promotes mineralisation. Deficiency in vitamin D leads to a reduction in calcium content in bone tissue.
Osteokalcin
Osteocalcin serves as an indicator of bone remodelling. It's produced in osteoblasts and chondrocytes, and it binds mineral components such as calcium and hydroxyapatite in organic bone matter.
Instructions before collection
We do not recommend entry of patients/clients with clinical signs of disease (temperature, cough, signs of respiratory tract infection, etc.) to undergo this test. We recommend hand disinfection prior to entry to the clinics/collection points.
It is advised to fast for a minimum of 8 hours by refraining from eating or drinking anything expect water. Faiing to fast before the test may affect result quality. If you are currently on medications, consult your healtcare provider to determine whether you should continue taking them prior to the test.
PREPARATION FOR BLOOD COLLECTION The recommended time to collect blood is between 7 a.m. and 9 a.m., to obtain comparable results from different blood draws. To assess the numerical test result, so-called reference intervals are used, which are based on morning fasting collections and are used for population comparison. This time interval is also recommended in light of the biological cycles that naturally take place in the body.
GENERAL PRE-SAMPLING INSTRUCTIONS • It is necessary to come to the testing site earlier, so that you can rest in the waiting room for approximately 20 minutes to have a relatively relaxed body and mind. • It is not advisable to draw blood before collection. • It is necessary to arrive on an empty stomach for the collection itself, in the case of collections at a later time in the day, at least three hours on an empty stomach. At home, it is desirable to drink a sufficient amount of pure water (at least up to half a liter) - this is important for a successful blood collection. Mineral water, juice, coffee and tea are not recommended. Herbs included in tea may contain substances affecting the blood count. Coffee and black tea increase gastric acid production and release insulin from the pancreas, thereby affecting glucose metabolism. Since everything in the body is interrelated, they can impact other tests. Another extreme is when your body is running out of fluids. In this case, the number of red blood cells, the level of protein and lipids bound to the protein increase and the level of urea in the blood can also increase. It is therefore advisable to drink pure water when you wake up.
Generally, it is recommended to: • around 6 p.m. eat only light meals, do not eat fatty food (cheese, butter, cream, meat, smoked meat, bacon) and sweet meals, • fast for 10-12 hours (Attention: it is not advisable to starve for more than 16 hours!), in the case of later collection (after 9:30 a.m.), a lighter breakfast is allowed, no later than 3 hours before collection, • drink non-alcoholic beverages and drinks without sugar in the usual quantity, in the case of adult clients 24 hours before blood collection (Alcohol in the blood changes lipid levels, the level of glucose is reduced, uric acid levels increase and liver enzymes are released into the blood), • take only prescribed medicines in the evening, • avoid increased physical activity, and strength and endurance exercise the day before blood collection (Lipid, glucose, some enzyme levels in the blood and other parameters may change during physical activity. The recovery of normal values to maintain the accuracy of laboratory results may take a longer time, depending on the duration of the exercise, your physical fitness in general and other factors. We recommend maintaining normal daily physical activity such as light stretching, short cycling to work, gardening, etc.), • avoid psychological stress, which raises blood glucose levels and causes the release of stress hormones in particular, • avoid smoking for at least 6 hours prior to blood collection because it increases the level of carbonylhemoglobin produced by the reaction of the blood dye with carbon monoxide and alters the permeability and elasticity of the vessels, affecting the ratios of blood analytes, • do not chew gum for at least 6 hours before blood collection, as this may affect glucose and enzyme levels, • do not undergo stressful diagnostic or therapeutic interventions for at least 24 hours prior to blood collection. If any of the tests you have selected require special preparation, you will be informed of the fact by email with the order and blood collection instructions attached. These specific instructions have priority over the general recommendations for preparation.
MEDICINES It is recommended to have blood collected before the planned doses of medicines. If it is not possible to take the medicine later, you should inform the nurse during blood collection and specify what medication you have taken. Take the medicines prescribed by your doctor in the morning or bring them with you to take them after blood collection (thyroid medicines, antihypertensive medicines, blood thinners, contraceptives, etc.) In the case of later collection (after 9:30 a.m.), you can take the prescribed medication in the morning. Do not take iron, vitamin, nutritional supplements or other supplements, including homeopathics, for at least three (3) days prior to blood collection.
SPECIFIC SITUATIONS In order to obtain the appropriate answers to your questions with regard to the laboratory tests, it is important to accurately notify the nurse at the healthcare provider about the following facts prior to your blood test: • regularly used medicines and supplements (ideally come with a written list to the blood collection site), • infectious diseases you suffer from (e.g., HIV, hepatitis, mononucleosis...), • contact with an infected person or presence in an infectious environment, • if you have received an infusion within the last 5 days, specify into which limb, • intramuscular injections within 3 days prior to the blood collection date, • long-term immobilisation, lost ability to move, • activities at higher altitudes, • allergy to common band-aids, • if you feel unwell when looking at blood or needles, please also notify our blood collection staff of the fact.
OTHER FACTORS Please note that prolonged use of medication or other important factors may affect the values measured by the tests you have selected. For more information, please see the description of the specific test. To obtain objective test results, take the time to properly prepare for your blood collection.
Parameters:
Calcium
Calcium is a mineral and also an essential building block of bones and teeth. It participates in the function of a number of enzymes, blood clotting, muscle function and the production and release of hormones.
Phosphate is an important mineral that helps with various functions, including bone health, teeth, energy production, and cell communication. Abnormal phosphate levels could indicate certain medical conditions or…
CBC allows to detect anemia and thus impaired oxygen supply to tissues, exclude infection or malfunction of the immune system and suspect blood clotting disorders or the risk of blood clots.
C-reactive protein (CRP) is a protein synthesised in the liver in response to an increase in plasma concentration of IL-6 in particular, and to a lesser extent other pro-inflammatory cytokines. It is one of the acute…
Vitamin D (calciferol) is present in humans in two different forms: vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol). You can use our test to measure your vitamin D blood level. Vitamin D3 production is…
ALT (Alanine aminotransferase) is an enzyme present in the cytoplasm of cells of certain tissues such as liver cells. It is important for the formation and degradation of amino acids, and also plays a role in nitrogen…
GGT is a gamma-glutamyl transferase, an enzyme bound to cell membranes with the highest concentration in the liver. It is very sensitive to changes in liver function, but also to damage to the biliary tract (for example…
Creatinine is a protein (protein) that is produced by all cells of the human body. Creatinine excretion takes place exclusively by the kidneys and therefore allows the examination of the level of creatinine in the blood…
Magnesium (Mg) is a mineral that is related to the metabolism of bones, muscles, intestines, kidneys and, together with other minerals, is involved in maintaining the balance of the internal environment. It helps the…
TSH is a hormone produced by the cells of the anterior lobe of the hypophysis/pituitary gland. It affects the metabolism of thyroid cells and stimulates the production and secretion of thyroid hormones, especially…
Follicle-stimulating hormone is a hormone produced in the anterior lobe of the pituitary gland. After menopause, levels of FSH in the blood can likely be elevated.
Luteinizing hormone is also a hormone produced in the anterior lobe of the pituitary gland. A typical finding in the postmenopausal period is an increased level of LH in the blood.
The bone health test analyzes bone metabolism and includes testing for calcium, phosphorus, vitamin D, hormone levels, and other key parameters to determine bone health. Between 7 and 25 parameters are tested, depending on the test variant.
Osteoporosis is asymptomatic for a long time and manifests itself with unnoticed rather than obvious symptoms. For example, losing a few centimeters of your height, changing your natural posture (you start to slouch, bend or lean forward), shortness of breath (compressed discs reduce lung capacity), and pain in the lumbar spine (1).
A guaranteed recipe is regular light exercise and sufficient calcium and vitamin D intake. Experts also recommend using protective equipment, e.g. during heavy work and sports, to prevent fractures. In all circumstances, follow an exercise and diet plan that benefits you, not makes you worse (1).
Arthrosis and osteoporosis are chronic diseases that affectthe skeletal system. Arthrosis is characterized by degenerative changes in bone cartilage, adjacent bone and joint capsule accompanied by limited mobility and joint pain. Osteoporosis develops due to thinning of the bone mass, which leads to an increased risk of fractures.
Treatment of osteoporosis depends on its cause. If the test shows a bone metabolism disorder, we recommend visiting a doctor who will determine the next course of action. Supplementation with vitamin D and calcium is important in preventing fractures; the dose and form will be recommended by your doctor.
If you suffer from osteoporosis, avoid oversalted foods, red meat, foods with added sugars, foods rich in oxalates (leafy vegetables and legumes), and wheat bran (the sulfur it contains increases the acidity of the body) (2).
At Unilabs, we offer a bone health examination, which includes a bone metabolism analysis, including testing calcium, phosphorus, vitamin D levels and hormone levels to determine bone health and possible imbalances in bone metabolism. The examination is suitable for people with musculoskeletal pain and a predisposition to osteoporosis.
If the results are not within the normal range, you should see a doctor who will recommend further examination necessary for the diagnosis of osteoporosis.
Bone is at its strongest from early adulthood until about age 30. Around age 35, bone begins to thin, with bone mass decreasing. This is true for everyone, but some people develop osteoporosis, where bone mass is lost much faster than normal, exponentially increasing the risk of fracture (3).
Bone health depends on a healthy diet that includes foods rich in protein and calcium, such as dairy products, leafy greens, and fortified cereals (4). Doctors also recommend eating enough calories to maintain a healthy weight and energy levels.
Customer reviews
5 stars out of 6 ratings
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Vlasta
·5/5
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Veľmi príjemný personál
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Ďakujeme za pozitívne hodnotenie, teší nás že ste boli spokojná. :)
08.01.2025
Alexander
·5/5
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všetko v poriadku
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Veľmi pekne Vám ďakujeme za pozitívne hodnotenie. :)
20.12.2024
Janka
·5/5
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Opakovane som s testami aj poskytnutými službami absolútne spokojná. Odporúčam.
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Veľmi pekne Vám ďakujeme za pozitívne hodnotenie, teší nás že ste boli spokojná s našimi službami. :)
19.10.2024
PETER
·5/5
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Znovu len sama chvala, odber na čas, vysledky v predstihu, mily personal.