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Antibody test - measles (Morbillivirus )
A serological test (from the blood) for IgG antibodies against the Morbillivirus that causes the disease. The result is a determination of whether the person has a high enough level of antibodies to be considered as protection against the disease. The test is not designed to diagnose acute disease because IgG antibodies are only produced in the interval after immunisation or after the disease has been overcome. Immunisation in the population is by blanket vaccination with a vaccine (called MMR - morbilli, mumps, rubella). Persons proven to have survived measles are immune to further infection. The level of protective antibodies gradually decreases with age.
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Antibody test - measles (Morbillivirus )
About this test
A serological test (from the blood) for IgG antibodies against the Morbillivirus that causes the disease. The result is a determination of whether the person has a high enough level of antibodies to be considered as protection against the disease. The test is not designed to diagnose acute disease because IgG antibodies are only produced in the interval after immunisation or after the disease has been overcome. Immunisation in the population is by blanket vaccination with a vaccine (called MMR - morbilli, mumps, rubella). Persons proven to have survived measles are immune to further infection. The level of protective antibodies gradually decreases with age.
Measles or morbilli is a viral infectious disease caused by an RNA virus of the genus Morbillivirus that causes a typical skin rash. They are extremely transmissible, making them one of the most contagious infectious diseases (1). Anyone who does not have measles antibodies or who has recently had the disease is susceptible (1).
What´s measured
Professionally about measles vaccination
Since 1969, measles vaccination was compulsory in Czechoslovakia. Today, the MMR vaccine, which combines vaccination against three diseases: measles, mumps and rubella, is used in Slovakia. Preschool children are vaccinated according to the current vaccination schedule (3).
One dose of the MMR vaccine has:
- 93 % efficacy against measles,
- 78 % efficacy against mumps and
- 97% efficacy against rubella (14).
Two doses of the MMR vaccine have:
- 97 % efficacy against measles and
- 88% efficacy against mumps (4).
Some people, even if they have received two doses of the vaccine, can get measles, mumps or rubella. The symptoms are milder and the disease is also less likely to spread further (4). The fact that an individual can get measles despite vaccination is due to a gradual decline in the level of protective antibodies (IgG class). Their level decreases with age (4) (5):
- between the ages of 25 and 29 years by 2%,
- between 30 and 34 years of age by 14 %,
- between 35 and 39 years of age by 17 %,
- between the ages of 40 and 44 by 23% (6).
People who have overcome measles are immune to further infection.
Persons born before 1969, before the introduction of universal measles vaccination, are naturally immune.(4)(7)(8) Persons with positive measles-specific IgG antibodies are considered immune. Persons with borderline or negative findings of IgG antibodies are considered non-immune (8). In the case of a negative IgG antibody finding, subsequent (re-)immunisation with a combination vaccine may be performed (6).
Interpretation of results
In case of purchasing the interpretation of the results, this interpretation is created by an internist from uLékaře.cz.
Collection instructions
Please read these instructions carefully well in advance of the collection.
Please bring a valid ID (ID card or passport) to verify your identity.
Testing procedure
How takes place Antibody test - measles (Morbillivirus )
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FAQ
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You can address your questions to info.sk@unilabs.online or to the sk.unilabs.online social media page. We will answer your questions on business days from 8:30 a.m. to 4:00 p.m.
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What is the preparation before blood collection?
You should arrive for your blood collection in the morning and on an empty stomach. It is also recommended to drink water before the blood collection. For more detailed information on how to prepare for a blood collection, please refer to the individual product pages in the Instructions Before Collection section and on the page the Instructions Before Collection.
How can I pay for the collection?
The payment is always made online via Unilabs Online. After entering your details, you will be redirected to the payment gateway, where you can confirm the payment with just a few clicks, and within a few minutes, you can proceed to your examination. You can use Apple Pay, Google Pay, or online card payment.
When will I know the results of the laboratory tests?
We will notify you immediately after the results are available in your account by email and possibly by text message, if you have a mobile phone number connected to your account.
Ms. Ivana says:
“The results arrived earlier, and the overall blood draw process was quick, so I’m satisfied. Online booking is great.”
In what form will I receive the results from sk.unilabs.online?
The results will be sent to your private sk.unilabs.online account in PDF version as soon as they are available. You will be informed about the availability of the result both by email and text message.
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Sources
(1) Spalničky. NZIP.cz. Dostupné online na: https://www.nzip.cz/clanek/35-spalnicky. [cit. 01-15-2025].
(2) Laboratory testing for measles. (2024). Measles (Rubeola). Dostupné online na: https://www.cdc.gov/measles/php/laboratories/index.html. [cit. 01-15-2025].
(3) Vyhláška č. 537/2006 Sb., o očkování proti infekčním nemocem, ve znění pozdějších předpisů. [cit. 01-15-2025].
(4) Professional, C. C. M. (2024c). MMR vaccine. Cleveland Clinic. Dostupné online na: https://my.clevelandclinic.org/health/procedures/mmr-vaccine. [cit. 01-15-2025].
(5) Bianchi, F. P., Mascipinto, S., Stefanizzi, P., De Nitto, S., Germinario, C., & Tafuri, S. (2021). Long-term immunogenicity after measles vaccine vs. wild infection: an Italian retrospective cohort study. Human Vaccines & Immunotherapeutics, 17(7), 2078–2084. Dostupné online na: https://doi.org/10.1080/21645515.2020.1871296. [cit. 01-15-2025].
(6) BÍLKOVÁ FRÁNKOVÁ, H., KLOUDOVÁ, A., ZELENÁ, H., TOMÁŠKOVÁ, H., ŠEBÁKOVÁ, H., MARTINKOVÁ, I., MATLEROVÁ, Š., FRÁNOVÁ, D., Jílková, E., Král, V. a kol. Víceúčelový sérologický přehled (spalničky, příušnice, petruse, virová hepatitida B) SP 2013, ČR: Závěrečná zpráva, příloha č.1. ZPRÁVY CENTRA EPIDEMIOLOGIE A MIKROBIOLOGIE, SZÚ. 2014, roč. 23, s. 1-152. [cit. 01-15-2025].
(7) Limberková, MUDr. & SZÚ Praha, NRL pro zarděnky, spalničky, parotitidu a parvovirus B19. (n.d.). Spalničky: odběr, skladování a transport klinického materiálu, laboratorní diagnostika, historie očkování. In KLINICKÝ MATERIÁL [Report]. Dostupné online na: https://www.khsova.cz/docs/01_aktuality/files/spalnicky_postup_odber.pdf. [cit. 01-15-2025].
(8) SZU, N. Z. (n.d.). LABORATORNÍ DIAGNOSTIKA SPALNIČEK. Dostupné online na: https://archiv.szu.cz/uploads/Epidemiologie/Spalnicky/Algoritmus_laboratorni_diagnostiky_spalnicek.pdf. [cit. 01-15-2025].