Liver, kidney and urinary tract examination (3in1)

Our kidney profile test measures overall kidney function indicating possible kidney disease or damage. Kidneys are filtering blood, eliminating waste through urine, regulating water retention, controlling ion concentrations, and maintaining the acid balance in the bloodstream.

Creatinine, a protein produced by all cells, is solely excreted by the kidneys, enabling examination of its blood levels and calculation of glomerular filtration for assessing renal function. eGFR estimates kidney function by approximating blood volume passing through kidney filters per minute. Urea, the end product of protein metabolism, is regulated by acid-base balance and reflects renal function, hydration, protein catabolism, and nitrogen levels. Electrolytes (sodium, chloride, potassium) help maintain internal balance, while calcium is crucial for bone, enzyme, clotting, muscle, and hormone functions. Phosphate supports bone, teeth, energy, and cell communication. Uric acid, a product of purine metabolism, acts as a potent antioxidant but may form tissue crystals with elevated levels.

Access valuable information about your kidney and bladder function with our Urin profile.

This test focuses on pH and specific gravity of urine, also includes qualitative evidence of the presence of protein, sugar, ketone bodies, bilirubin, urobiliinogen, nitrites, hemoglobin and leukocytes in the urine. It provides insight into the cellular, organic and inorganic composition of urine. It is important for assessing kidney and bladder function.

Benefits of liver, kidney and urinary tract testing (3in1)

• 21 parameters measured (e.g. bilirubin, calcium, sodium, creatinine, phosphorus or ALT)
• Results within 2 working days
• 3 tests in 1
• Valuable information about the state of your liver, kidneys and bladder thanks to our comprehensive text
• Get an overview of the condition of your organs

What´s measured

Parameters

ALT

ALT (alanine aminotransferase) is an enzyme present in the cytoplasm of cells of certain tissues such as liver cells. It is important for the formation and degradation of amino acids, and also plays a role in nitrogen metabolism, but also glucose.

AST

Aspartate aminotransferase is another liver enzyme that is elevated when the liver cell - hepatocyte - is damaged. The most common causes of liver damage include ethanol (alcohol), fatty liver or viral hepatitis. Ureais the end product of nitrogen metabolism of amino acids. It is formed in the liver.

ALP

ALP activity and osteocalcin levels will provide information about your bone metabolism.

GGT

GGT is a gamma-glutamyl transferase, an enzyme bound to cell membranes with the highest concentration in the liver. It is very sensitive to changes in liver function, but also to damage to the biliary tract (for example, as a result of drug or alcohol damage).

Total proteins

Total protein determination is the determination of the concentration of all proteins in blood plasma. Proteins are the basic building blocks of all cells and tissues. They are important not only for body growth, but also perform a number of the following functions - transport of all substances insoluble in water, maintaining oncotic pressure in cells, maintaining proper blood pH.

Albumin

Albumin is a type of protein in your blood that helps maintain fluid balance, transports substances in your body, and is produced by the liver.

Direct bilirubin

Direct bilirubin has been processed by the liver and is ready to be eliminated from the body. Bilirubin is a yellowish pigment produced when red blood cells break down. It is processed by the liver and converted into direct bilirubin, which is then excreted through bile into the intestines and eventually eliminated from the body. Elevated levels of direct bilirubin can indicate liver or gallbladder problems.

Total bilirubin

Total bilirubin refers to the combined measurement of both direct bilirubin and indirect bilirubin in the blood. Bilirubin is a yellow pigment produced when red blood cells break down. Indirect bilirubin is the form of bilirubin that has not yet been processed by the liver. It travels through the bloodstream to the liver, where it is converted into direct bilirubin. It can help assess the liver or gallbladder conditions.

Globulin

Globulin is a group of proteins found in your blood. It plays an essential role in various functions in your body, such as immune system support, blood clotting, and transport of hormones and vitamins. Abnormal globulin levels can indicate certain medical conditions, such as liver disease, immune disorders, or malnutrition."

The albumin/globulin ratio

The albumin/globulin ratio compares the levels of two types of proteins in your blood: albumin and globulins. Albumin is a specific protein, while globulins are a group of proteins that include antibodies and other important proteins for various functions in the body. An abnormal albumin/globulin ratio may indicate certain health conditions or imbalances in your body.

Creatinine

Creatinine is a protein (protein) that is produced by all cells of the human body. Creatinine excretion takes place exclusively by the kidneys and therefore allows the examination of the level of creatinine in the blood and the calculation of glomerular filtration to reveal disorders of renal function.

eGFR

eGFR, or estimated Glomerular Filtration Rate, is a measurement used to estimate how well your kidneys are functioning. It provides an approximation of the amount of blood that passes through the tiny filters in the kidneys each minute. A higher eGFR indicates better kidney function, while a lower eGFR may suggest impaired kidney function and the need for further evaluation.

Urea

Urea is the end product of protein metabolism. It is formed as a result of the removal of split nitrogen from amino acids in the form of ammonia, which is toxic to the central nervous system, to the liver and kidneys. The urea cycle takes place in the liver and urea is then released into the bloodstream and transported to the kidneys, where it is filtered into the urine or reabsorbed. The production of urea is affected by the state of acid-base balance of the organism. Its concentration in the blood depends on the intake of protein in the diet and overall metabolism. The test is suitable as an indicator of renal function, the degree of hydration of the body, protein catabolism, to determine the level of nitrogen.

Water forms the basis of the internal environment. Disturbances in water metabolism and fundamental ions (Na, K Cl) are common. Sodium is the main cation and binds the most water. The determination of sodium ions in the blood is used to detect hyponatremia or hypernatremia accompanied by dehydration, swelling. In contrast, chlorides (Cl) are the main anion and their level is increasing as the level of sodium is decreasing, and vice versa. It participates in maintaining a constant internal environment, such as osmotic pressure or acid-base balance. Potassium is the main ion inside cells. It works with sodium and chlorides to regulate the amount of fluid in the body, stimulate muscle contraction and maintain acid-base balance.

Calcium

Calcium is a mineral and also an essential building block of bones and teeth. It participates in the function of a number of enzymes, blood clotting, muscle function and the production and release of hormones.

Phosphate

Phosphate is an important mineral that helps with various functions, including bone health, teeth, energy production, and cell communication. Abnormal phosphate levels could indicate certain medical conditions or imbalances in your body.

Uric acid

Uric acid is a nitrogenous substance that is formed in humans as the product of purine metabolism. It is a powerful antioxidant (it captures free oxygen radicals). It is one of the parameters in metabolic syndrome. When increasing its content in the body, it can be deposited in the form of crystals in the tissues.

Urine analysis

Urine analysis (Urine chemistry test and Urine sediment) focuses on pH and specific gravity of urine, also includes qualitative evidence of the presence of protein, sugar, ketone bodies, bilirubin, urobiliinogen, nitrites, hemoglobin and leukocytes in the urine. It provides insight into the cellular, organic and inorganic composition of urine. It is important for assessing kidney and bladder function.