HBsAg
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HBsAg

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HBsAg (hepatitis B surface antigen) is a surface antigen of the hepatitis B virus that can be detected in the serum of infected individuals. A positive HBsAg result indicates infection with the hepatitis B virus, which causes viral infectious inflammation of the liver – viral hepatitis B (type B jaundice). The disease is transmitted through blood and sexual contact, but can also be passed from mother to child during pregnancy or childbirth.

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About this test

HBsAg (hepatitis B surface antigen) is a surface antigen of the hepatitis B virus that can be detected in the serum of infected individuals. A positive HBsAg result indicates infection with the hepatitis B virus, which causes viral infectious inflammation of the liver – viral hepatitis B (type B jaundice). The disease is transmitted through blood and sexual contact, but can also be passed from mother to child during pregnancy or childbirth.

HBsAg is present in the serum during acute infection, and if the disease becomes chronic, HBsAg persists in the serum. The presence of HBsAg in the serum for more than 6 months after exposure to the virus suggests a chronic infection or chronic asymptomatic carrier status.

Further tests are required to distinguish between acute hepatitis B and the reactivation of chronic hepatitis B. The presence of Anti HBc IgM antibodies indicates acute hepatitis B. During the replicative phase of the infection (viral replication), HBeAg and positive HBV DNA are also usually present.

Testing for HBsAg, together with testing for total Anti HBc, is recommended as a screening test for hepatitis B virus infection; to confirm or rule out infection, further serological markers of hepatitis B virus infection—in particular HBV DNA and HBeAg—must be tested for if the result is positive. For screening aimed at preventing transmission of the infection via blood transfusion, tissue and organ transplantation, among healthcare workers and pregnant women, HBsAg testing is sufficient; however, in the event of a positive result, testing for other hepatitis B markers should also be carried out.

Notice

Laboratory test results must always be interpreted in the context of the patient’s medical history, clinical condition, and the results of other laboratory and diagnostic tests. Deviations from normal values are not sufficient on their own to establish a diagnosis, and values within the normal range do not always mean that a disease is absent. It is advisable to consult a doctor about the results.

Suitable for

For anyone who wants to find out whether they are infected with the hepatitis B virus, even if they have no symptoms.

Hepatitis B screening (Anti HBs and total Anti HBc must also be tested)

This may be particularly suitable for people with piercings or tattoos, those who have had unprotected sex, those with multiple sexual partners, and those who inject drugs.

In cases of suspected acute hepatitis B, which may present, for example, with jaundice (yellowing of the skin and whites of the eyes), fatigue, nausea, vomiting, abdominal pain (particularly under the right rib cage), dark urine and pale stools.

If liver disease is suspected.

Collection instructions

Please read these instructions carefully well in advance of the collection.

Bring a valid ID (ID card or passport) to verify your identity.

Testing procedure

How takes place HBsAg

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Explore our wide selection of lab tests tailored to your symptoms, lifestyle, or specific parameters. Find exactly what you need — quickly and easily.

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Select a convenient time at one of our 41 collection points and pay securely by card. The whole process takes just minutes.

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Visit your chosen collection point

Arrive at your selected location at the scheduled time. The sample collection is fast and hassle-free.

We’ll collect: blood.

4

Expert laboratory analysis

Your sample is analyzed in top-tier, accredited labs using state-of-the-art technology. Results are available within 3 business days.

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Get your results online

Access your results safely and securely in your personal account. Clearly presented and easy to understand.

Symptoms of acute viral hepatitis B

An acute hepatitis B virus infection may be asymptomatic in many of those infected. In some patients, it may progress to a chronic stage, even in the absence of symptoms during the acute phase. Patients with chronic hepatitis B are often unaware of their condition because they have no symptoms. However, they are a source of infection for others. In some patients, chronic hepatitis can progress and lead to cirrhosis and liver cancer.

If acute hepatitis does present with symptoms, these may include:

  • jaundice (yellowing of the skin and the whites of the eyes),
  • fatigue,
  • nausea and vomiting,
  • abdominal pain (particularly under the right rib cage),
  • dark urine and pale stools,
  • flu-like symptoms,
  • joint pain,
  • skin and neurological symptoms.

FAQ

What is the preparation before blood collection?

You should arrive for your blood collection in the morning and on an empty stomach. It is also recommended to drink water before the blood collection. For more detailed information on how to prepare for a blood collection, please refer to the individual product pages in the Instructions Before Collection section and on the page the Instructions Before Collection.

How can I pay for the collection?

The payment is always made online via Unilabs Online. After entering your details, you will be redirected to the payment gateway, where you can confirm the payment with just a few clicks, and within a few minutes, you can proceed to your examination. You can use Apple Pay, Google Pay, or online card payment.

In what form will I receive the results from sk.unilabs.online?

The results will be sent to your private sk.unilabs.online account in PDF version as soon as they are available. You will be informed about the availability of the result both by email and text message.

When will I know the results of the laboratory tests?

We will notify you immediately after the results are available in your account by email and possibly by text message, if you have a mobile phone number connected to your account.

Ms. Ivana says:
“The results arrived earlier, and the overall blood draw process was quick, so I’m satisfied. Online booking is great.”

Can I contact a helpline if I have a question?

You can address your questions to [email protected] or to the sk.unilabs.online social media page. We will answer your questions on business days from 8:30 a.m. to 4:00 p.m.

Our info line is receiving more and more praise. Here is one of them:
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Sources

  1. Paraličová Z., Schréter I. Akútne vírusové hepatitídy. Štandardné postupy. Infektológia https://www.health.gov.sk/?Standardne-Postupy-V-Zdravotnictve 
  2. Vírusová hepatitída typu B (žltačka typu B). Úrad verejného zdravotníctva SR.  https://www.uvzsr.sk/web/uvz/virusova-hepatitida-typ-b-zltacka-typu-b 
  3. Hepatitis B. Dostupné online na: https://www.who.int/news-room/fact-sheets/detail/hepatitis-b, navštívené: 30. 7. 2026